Hey Everyone,Lets talk about Typhoid Fever
What is typhoid
fever?
Typhoid fever is an acute illness associated with fever
caused by the Salmonella typhi bacteria. It can also be caused by Salmonella
paratyphi, a related bacterium that usually causes a less severe illness. The
bacteria are deposited in water or food by a human carrier and are then spread
to other people in the area. Typhoid fever affects more than 21 million people
annually, with about 200,000 people dying from the disease. In Nigeria precisely,
most people mistook thyphoid as malaria and thereby not getting the required
and specific treatment to eliminate in totally.
How Do People Get
Typhoid Fever?
Typhoid fever is contracted by drinking or eating the
bacteria in contaminated food or water. People with acute illness can
contaminate the surrounding water supply through stool, which contains a high
concentration of the bacteria. Contamination of the water supply can, in turn,
taint the food supply. The bacteria can survive for weeks in water or dried
sewage.
About 3%-5% of people become carriers of the bacteria after
the acute illness. Others suffer a very mild illness that goes unrecognized.
These people may become long-term carriers of the bacteria -- even though they
have no symptoms -- and be the source of new outbreaks of typhoid fever for
many years.
How Is Typhoid Fever
Detected?
After the ingestion of contaminated food or water, the bacteria gets into the small intestine and
enter the bloodstream temporarily. The bacteria are carried by white blood
cells in the liver, spleen, and bone marrow, where they multiply and reenter
the bloodstream. People develop symptoms, including fever, at this point.
Bacteria invade the gallbladder, biliary system, and the lymphatic tissue of
the bowel. Here, they multiply in high numbers. The bacteria pass into the
intestinal tract and can be identified in stool samples. If a test result isn't
clear, blood samples will be taken to make a diagnosis..
What Are the Symptoms
of Typhoid Fever?
The breeding period is usually 1-2 weeks, and the duration of the
illness is about 3-4 weeks. Symptoms include:
Poor appetite
Headaches
Generalized aches and pains
Fever as high as 104 degrees Farenheit
Lethargy
Diarrhea
and abdominal pain
and discomfort are common. The fever becomes constant. Improvement occurs in
the third and fourth week in those without complications.
How Is Typhoid Fever
Treated?
Typhoid fever is treated with antibiotics which kill the
Salmonella bacteria. Prior to the use of antibiotics, Several antibiotics are
effective for the treatment of typhoid fever. Chloramphenicol was the original
drug of choice for many years. Because of rare serious side effects,
chloramphenicol has been replaced by other effective antibiotics.
Commonly prescribed
antibiotics
Ciprofloxacin
(Cipro). In the United States, doctors often prescribe this for nonpregnant
adults.
Ceftriaxone (Rocephin). This injectable
antibiotic is an alternative for people who may not be candidates for
ciprofloxacin, such as children,
In Nigeria, Drugs like Amoxil Beecham is one of the major
drugs used for this defect. Drugs also includes
Amoxicillin
(Trimox, Amoxil, Biomox)
Trimethoprim and
sulfamethoxazole (Bactrim DS, Septra)
Ciprofloxacin (Cipro)
Azithromycin
(Zithromax)
Ceftriaxone (Rocephin)
Ofloxacin (Floxin)
Levofloxacin
(Levaquin)
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